RAF Typhoon FGR4s have operated alongside French aircraft in a coordinated attack against an underground arms cache in Syrian territory employed by the Daesh militant organization, per a report from the UK's MoD.
The site, located using surveillance, was believed to be housing weapons and explosive materials, the statement said, and was positioned in mountainous terrain just above the historic site of Palmyra in Syria's central region.
"Our aircraft used Paveway IV guided bombs to strike a series of entry passages leading to the facility... early reports indicate the objective was successfully hit," the ministry announced.
There was no sign of any harm to civilians in the strike conducted Saturday night and each participating jet returned safely, the defence officials confirmed.
The Typhoon fighters were supported by a Voyager aerial refuelling aircraft.
Daesh - referred to as Daesh - enforced extremist governance over parts of both Syria and Iraq until 2019.
"This action shows the UK's leading role, and determination to work closely with our allies, to stamp out any resurgence of Daesh and their harmful and extremist ideologies in the Middle East," Britain's Defence Chief the minister said.
RAF aircraft have performed overwatch operations over Syria to "prevent any attempted resurgence" of IS subsequent to its military defeat at the climactic battle in Baghuz in the year 2019, the MoD reported.
"I extend gratitude to all the members of our armed forces participating in this operation for their skill and their courage," he added. "Including them were thousands of British personnel stationed over the holidays. This action, to remove dangerous terrorists who threaten our way of life, shows how UK forces are prepared to act, all year round, ensuring Britain's security at home and strong abroad."
Last December, the American forces carried out what it described as a "massive strike" against Daesh sites in the country, subsequent to an attack resulted in the deaths of two American soldiers and a local interpreter in Palmyra.
The U.N. reports Islamic State still maintains roughly 5-7 thousand militants in Syria and Iraq.